Research Use Only

GHRP-6 — Growth Hormone Releasing Peptide-6

A synthetic hexapeptide ghrelin receptor agonist studied for its ability to stimulate growth hormone release from the anterior pituitary in research models.

Growth HormoneMuscle Growth

Reconstituted for research use • Per research protocol

In Stock
Single Vial Pack of 10

GHRP-6

CAS #: 87616-84-0
$38 and up
Ships today · Research use only
Apr 13
Ordered
Apr 14-15
Shipped
Apr 20-24
Delivered

Compound Details

Formula C46H56N12O6
Molecular Weight 873.01 g/mol
CAS Number 87616-84-0
Appearance White lyophilized powder

Mechanism of Action

GHRP-6 binds to ghrelin receptors (GHS-R1a) on anterior pituitary somatotroph cells, triggering growth hormone release through a pathway independent of GHRH signaling. This dual mechanism allows for synergistic effects when combined with GHRH analogs in research protocols.

Overview

GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that acts as a potent agonist of the growth hormone secretagogue receptor (GHS-R1a), also known as the ghrelin receptor. It was among the earliest growth hormone secretagogues investigated in research settings and remains widely studied today. In preclinical research, GHRP-6 has been shown to stimulate growth hormone release from the anterior pituitary gland through a mechanism distinct from growth hormone-releasing hormone (GHRH). Beyond GH secretion, research has examined its effects on appetite stimulation via the ghrelin pathway, promotion of gastric motility, and potential cardioprotective properties. GHRP-6 is frequently studied alongside GHRH analogs such as CJC-1295 for synergistic growth hormone release, as the two peptides act through complementary receptor pathways. For research use only. Not intended for human consumption.

Pricing

5mg lyophilized vial $38
10mg lyophilized vial $50

Volume pricing available — create an account to see tiered rates.

Purity & Testing

COA available. Third-party testing by Finnrick Analytical.

Certificates of Analysis (COA) are available in your account. Third-party testing is conducted to verify identity, purity, and potency.

Storage & Handling

Store lyophilized at -20°C or 2-8°C. Reconstituted: 2-8°C, use within 30 days.

Shipping

Ships worldwide from 6 distribution centers via USPS Ground Advantage

Available for direct research purchase

Research-use-only products are sold strictly for laboratory and research purposes. By purchasing, you acknowledge that these products are not intended for human or veterinary use, and you agree to PharmaOrder's RUO terms of service.

Published Research

Selected peer-reviewed studies referenced in this product overview.

Growth hormone-releasing peptide-6 stimulates GH release in humans through a mechanism independent of GHRH
Bowers CY, Reynolds GA, Durham D, et al. — Journal of Clinical Endocrinology & Metabolism (1990)
Established that GHRP-6 stimulates GH release through a receptor pathway distinct from GHRH, enabling synergistic effects when combined.
Ghrelin mimetics and GH secretagogues: potential therapeutic applications
Arvat E, Maccario M, Di Vito L, et al. — Endocrine Reviews (2001)
Comprehensive review of GH secretagogues including GHRP-6, covering receptor pharmacology, clinical effects, and therapeutic potential.
GHRP-6 acts at the hypothalamus and the pituitary to produce growth hormone release
Popovic V, Damjanovic S, Micic D, et al. — Journal of Clinical Endocrinology & Metabolism (1995)
Demonstrated dual site of action for GHRP-6 at both hypothalamic and pituitary levels for GH release in humans.

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FAQ

What is GHRP-6?
GHRP-6 is a synthetic hexapeptide that acts as a ghrelin receptor (GHS-R1a) agonist. It was one of the earliest growth hormone secretagogues studied in research and stimulates GH release from the anterior pituitary through a pathway independent of GHRH.
How does GHRP-6 differ from GHRH analogs like CJC-1295?
GHRP-6 acts on ghrelin receptors (GHS-R1a) while CJC-1295 acts on GHRH receptors. These distinct pathways are complementary, which is why they are often studied together for synergistic growth hormone release in research models.
Does GHRP-6 affect appetite in research models?
Yes. Because GHRP-6 activates ghrelin receptors, research has shown it can stimulate appetite and promote gastric motility in preclinical models. This distinguishes it from some other GH secretagogues like ipamorelin, which have minimal ghrelin-related effects.
How should GHRP-6 be stored?
Store lyophilized GHRP-6 at -20°C for long-term storage or 2-8°C for short-term. Once reconstituted, keep refrigerated and use within 30 days for optimal stability.
Editorial Review
Updated March 2026. Reviewed against product catalog, quality, and fulfillment standards. This page is educational and not instructions for human use. See our editorial standards and quality process.

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