GHK-Cu delivers bioavailable copper to cells and activates tissue remodeling pathways. It upregulates collagen, elastin, and glycosaminoglycan synthesis while promoting antioxidant enzyme expression (SOD, catalase). The copper moiety is essential for lysyl oxidase activity, which cross-links collagen and elastin fibers.
GHK-Cu — Copper Tripeptide Complex Research Peptide
A naturally occurring copper tripeptide complex studied for its effects on tissue remodeling, collagen synthesis, and cellular longevity pathways.
CAS 49557-75-7 • 403.92 g/mol • Prepared for research use • Per research workflow
GHK-Cu Structure
Reference identifiers are batch-specific for coded materials and are documented on the lot COA/SDS rather than inferred or estimated.
Mechanism of Action
GHK-Cu Overview
GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper tripeptide found in human plasma, saliva, and urine. Plasma levels of GHK-Cu decline significantly with age, from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60. In research, GHK-Cu has been studied extensively for its roles in tissue remodeling, collagen and elastin synthesis, and anti-inflammatory signaling. It has demonstrated the ability to activate genes involved in tissue remodeling while suppressing genes associated with tissue degradation and inflammation. GHK-Cu is also studied for its antioxidant properties and its ability to promote decorin expression, which plays a role in extracellular matrix organization and tissue integrity.
Purity & Testing
GHK-Cu is listed as 50mg lyophilized vial; 100mg lyophilized vial. Catalog identity: CAS 49557-75-7; formula C14H24CuN6O4; molecular weight 403.92 g/mol. The lot COA for GHK-Cu is available in your account. Finnrick Analytical performs HPLC purity analysis and mass spectrometry identity confirmation on that lot.
- Catalog configurations: 50mg lyophilized vial, 100mg lyophilized vial
- CAS: 49557-75-7
- Formula: C14H24CuN6O4
- Molecular weight: 403.92 g/mol
See the GHK-Cu COA page.
Storage & Handling
Store lyophilized powder at -20°C or 2-8°C, protected from light.
Shipping
Ships worldwide from 6 distribution centers via USPS Ground Advantage
Available for direct research purchase
Research-use-only products are sold strictly for laboratory and research purposes. By purchasing, you acknowledge that these products are not intended for human or veterinary use, and you agree to PharmaOrder's RUO terms of service.
Published Research
Selected peer-reviewed studies referenced in this product overview.
FAQ
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