Research Use Only
AOD-9604
A synthetic peptide fragment of human growth hormone (amino acids 177-191) studied for its role in fat metabolism and lipolysis without affecting blood sugar or growth.
Weight ManagementMetabolic Research
Starting at $24
Pricing
5mg
$24
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6 distribution centers
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Research Grade
≥98% HPLC purity
Apr 13
Ordered
Apr 14-15
Shipped
Apr 20-24
Delivered
Route
Reconstituted for research use
Frequency
Per research protocol
Shipping
Ships worldwide from 6 distribution centers via USPS Ground Advantage
Quality
COA available. Third-party testing by Finnrick Analytical.
Compound
CAS
221231-10-3
Mechanism of Action
AOD-9604 mimics the lipolytic region of human growth hormone by activating beta-3 adrenergic receptors on adipocytes. This triggers a signaling cascade that stimulates hormone-sensitive lipase, accelerating the release of stored fatty acids from fat cells for oxidation. Crucially, the peptide does not bind the full HGH receptor, so it does not promote cell proliferation, skeletal growth, or insulin resistance — isolating the fat metabolism pathway from other growth hormone effects.
Storage & Handling
Store lyophilized at -20°C or 2-8°C. Reconstituted: 2-8°C, use within 30 days.
Published Research
Metabolic study of the lipolytic fragment (AOD9604) of human growth hormone
Heffernan MA, Thorburn AW, Fam B, et al. — Obesity Research (2001)
Effects of an oral formulation of the hGH fragment AOD9604 on fat metabolism in Zucker diabetic fatty rats
Heffernan MA, Jiang WJ, Thorburn AW, Ng FM. — Obesity (2003)
A double-blind, placebo-controlled study of the safety and efficacy of a novel anti-obesity drug (AOD9604)
Stier H, Vos E, Kenley D. — Journal of Endocrinology and Metabolism (2013)
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FAQ
Frequently Asked Questions
What is AOD-9604?
AOD-9604 is a synthetic peptide fragment corresponding to amino acids 177-191 of human growth hormone, with an added tyrosine at the N-terminus. It was originally developed as an anti-obesity drug candidate and is studied for its lipolytic properties.
How does AOD-9604 differ from HGH?
AOD-9604 retains only the fat metabolism region of growth hormone. It does not affect IGF-1 levels, blood sugar, or cell growth. This selective profile allows researchers to study lipolysis without the confounding variables of full-length HGH.
How should AOD-9604 be stored?
Store lyophilized AOD-9604 at 2-8 degrees C for optimal stability. Once reconstituted with bacteriostatic water, refrigerate and use within 28 days. Avoid repeated freeze-thaw cycles.