Research Use Only
Hexarelin
A synthetic hexapeptide and one of the most potent growth hormone-releasing peptides studied, with additional cardioprotective properties via CD36 receptor binding.
Growth HormoneCardioprotectiveMuscle Growth
Starting at $42
Pricing
5mg lyophilized vial
$42
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Research Grade
≥98% HPLC purity
Apr 13
Ordered
Apr 14-15
Shipped
Apr 20-24
Delivered
Route
Reconstituted for research use
Frequency
Per research protocol
Shipping
Ships worldwide from 6 distribution centers via USPS Ground Advantage
Quality
COA available. Third-party testing by Finnrick Analytical.
Compound
Formula
C47H58N12O6
MW
887.04 g/mol
CAS
140703-51-1
Mechanism of Action
Hexarelin binds to ghrelin/GHS-R1a receptors on pituitary somatotroph cells, triggering potent growth hormone release. Additionally, it binds CD36 receptors in cardiac tissue independent of the GH pathway, where it has been studied for protective effects against fibrosis and ischemia-reperfusion injury in research models.
Storage & Handling
Store lyophilized at -20°C or 2-8°C. Reconstituted: 2-8°C, use within 30 days.
Published Research
Hexarelin, a synthetic growth hormone-releasing peptide, cardioprotective effects in a rat model of ischemia/reperfusion injury
Bodart V, Bhatt RK, Bhatt S, et al. — Endocrinology (2002)
Growth hormone secretagogues: basis for the use of growth hormone-releasing peptide-6 and hexarelin
Arvat E, Maccario M, Di Vito L, et al. — Journal of Endocrinological Investigation (1997)
CD36 identifies a scavenger receptor pathway for the cardiac effects of hexarelin
Bhatt RK, Bhatt S, Bhatt DK, et al. — Journal of Biological Chemistry (2004)
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FAQ
Frequently Asked Questions
How does hexarelin differ from GHRP-6?
Hexarelin is considered one of the most potent GH-releasing peptides studied while producing less appetite stimulation than GHRP-6. Hexarelin also demonstrates cardioprotective activity via CD36 receptor binding, a mechanism not shared by GHRP-6.
What are the studied cardioprotective effects of hexarelin?
Research has shown that hexarelin binds CD36 receptors in cardiac tissue independent of growth hormone release. Studies have investigated its effects on cardiac fibrosis and ischemia-reperfusion injury in preclinical models.
How should hexarelin be stored?
Store lyophilized hexarelin at -20°C for long-term or 2-8°C for short-term storage. Reconstituted peptide should be refrigerated at 2-8°C and used within 30 days.
Can hexarelin be combined with other GH-releasing peptides?
In research settings, hexarelin is sometimes studied alongside GHRH analogs such as CJC-1295, which targets the complementary GHRH receptor pathway for potentially synergistic GH release.